Biomanufacturing

Novel Delivery of Antibodies Fights HIV

DNA delivered to cells via electrical pulses was first explored for creating new vaccines and is now being tested in the lab to produce disease-fighting proteins.

Melissae Fellet
October 15, 2018
Man-Made Platelets May Revolutionize Cancer Treatment

Platelet BioGenesis built a device that makes platelets. The process could revolutionize blood transfusions and cancer treatment.

Lina Zeldovich
October 15, 2018
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ASME TechCast: #2: How to Close the Engineering Communication Gap

In episode 2 of ASME TechCast, we explore the communication gap that often exists between engineers and their colleagues, especially clinicians and others in the biomedical industry. We also discuss the new lexicon that members of the Alliance of Advanced Biomedical Engineering (AABME.org) are rolling out to help solve that problem. 

Jeff O'Heir
October 01, 2018
Creation of Beating Heart Parts Could Lead to New Treatments

Researchers moved closer to solving problems with treating heart disease by developing ways to build tissues and parts of a human heart using human stem cells.

Melissa Lutz Blouin
September 24, 2018
3D Bioprinting Improves Speed and Quality of Tissue Engineering

Engineers have developed a new process of 3D bioprinting tissues that uses multiple cell-based inks to create more realistic structures in less time than previous methods.

Melissae Fellet
September 10, 2018
WEBINAR: Biomanufacturing of Pluripotent Stem Cells and Their Differentiated Progenies in Integrated Bioprocesses

Cell therapy manufacturing is a new discipline where production of adult and pluripotent stem cell types are required for cell therapies. Several hundreds of clinical trials with adult mesenchymal stem cells for therapies such as auto-immune diseases, bone, cartilage repair and stroke are looking promising. For the pluripotent stem cell therapies, retinal pigment epithelial cells, pancreatic islet progenitors and neurons are being applied for treating blindness, diabetes and Parkinson’s disease in early stage clinical trials.

September 10, 2018
New Funding Increases Access to Hot Cryo-EM Microscopy Technology

Scientists and bioengineers are warming up to cryogenic electron microscopy (cryo-EM), an ultra-low-temperature technique for visualizing the atomic-level inner workings of human cells and other applications.

Michael MacRae
July 09, 2018
AABME CONNECT: Industry Looks to Take Modeling to Next Level

It’s no secret that most biomedical firms today use modeling to make research and development decisions. What remains to be seen is how to take modeling, within companies and among regulatory agencies, to the next level.

Alan Brown
June 25, 2018
AABME CONNECT: Building Trust in Computer Modeling and Simulation

Medical device makers lag other industries in their use of computer models. One of the big issues discussed at AABME CONNECT is how much can researchers, regulators, and engineers trust their models and simulation?

Alan Brown
June 11, 2018
Heart-On-A-Chip Achieves Faster Delivery Time

Columbia University researchers recently generated beating cardiac tissue from induced pluripotent stem cells, human cells that are able to differentiate into nearly any cell type. Using physical conditioning, the researchers produced samples with the hallmarks of mature heart tissue with just four weeks of cell culture. The work paves a concrete pathway to functional heart-on-a-chip platforms.

Menaka Wilhelm
May 21, 2018
Injectable Bandage Stops Internal Bleeding of Severe Wounds

Biomedical engineers at Texas A&M University developed a hydrogel made from nanoflakes of synthetic clay and sugar chains extracted from seaweed. The gel could act as an injectable bandage to stop internal bleeding on a battlefield, in a surgical suite, or at an accident site.

Melissae Fellet
May 14, 2018
Bioprinting Better Artificial Joints

Lorenzo Moroni and his team at University of Maastricht's Institute for Technology-Inspired Regenerative Medicine (MERLN) in The Netherlands, use 3D bioprinting to create "smart scaffolds," which they seed with patient stem cells and growth factors to produce structures that behave like natural cartilage tissues.

Melissa Lutz Blouin
April 30, 2018
Push to Scale Up Cell Therapy Manufacturing

Cellular Biomedicine Group, a clinical-stage biopharmaceutical company that develops immunotherapies for cancer and stem cell therapies for degenerative diseases, recently partnered with GE Healthcare to build a platform to produce therapies at scale for clinical trials. Aims to solve challenge of developing enough genetically modified cells to test products on large populations.

Menaka Wilhelm
April 30, 2018
Bacteria Opens Vents to Release Sweat from Athletic Shirt

Bioengineer, entrepreneur, MIT grad, designer Wen Wang invented an athletic-wear fabric that uses bacteria-activated vents to cool down the wearer.

Mark Crawford
April 23, 2018