Georgia Tech researchers have developed a way to remotely activate the modified T cells from outside the body using a near-infrared laser that very precisely targets cancerous tumors.
Ronald Zuckermann, director of the Molecular Foundry at Lawrence Berkeley National Laboratory, and his colleagues have created a two-dimensional sugar-coated nanosheet that mimics the surface of cells and, in doing so, can selectively target pathogens like viruses and bacteria.
Gain access to free tools and resources from AABME, an initiative designed to stimulate biomedical innovation by bringing together and providing resources to the biomedical engineering community.
It’s no secret that most biomedical firms today use modeling to make research and development decisions. What remains to be seen is how to take modeling, within companies and among regulatory agencies, to the next level.
Scientists at Harvard’s Wyss Institute for Biologically Inspired Engineering have transformed CRISPR into a powerful mutation surveillance and disease prevention tool.
After a decade of work in his lab at the Howard Hughes Medical Institute, Eric Betzig has developed a microscope that presents an unprecedented picture of subcellular activity in 3D living color.
A new device captures circulating tumor cells (CTCs) in the blood stream, providing a new avenue for early detection of metastatic cancer, as well as opportunities to test the source of the cells or the effectiveness of ongoing treatment.
Columbia University researchers recently generated beating cardiac tissue from induced pluripotent stem cells, human cells that are able to differentiate into nearly any cell type. Using physical conditioning, the researchers produced samples with the hallmarks of mature heart tissue with just four weeks of cell culture. The work paves a concrete pathway to functional heart-on-a-chip platforms.
Columbia University engineers use a soft mesh scaffold to produce a dramatically higher amount of functional T cells from blood taken from leukemia patients.
Harvard professor George Church discusses advances in portable genome monitoring as well as recent developments in the anti-aging therapies for which is he is so well known.
Lorenzo Moroni and his team at University of Maastricht's Institute for Technology-Inspired Regenerative Medicine (MERLN) in The Netherlands, use 3D bioprinting to create "smart scaffolds," which they seed with patient stem cells and growth factors to produce structures that behave like natural cartilage tissues.
Cellular Biomedicine Group, a clinical-stage biopharmaceutical company that develops immunotherapies for cancer and stem cell therapies for degenerative diseases, recently partnered with GE Healthcare to build a platform to produce therapies at scale for clinical trials. Aims to solve challenge of developing enough genetically modified cells to test products on large populations.
Joseph Wu Director of the Stanford Cardiovascular Institute and Professor of Medicine and Radiology at Stanford University, discusses the rise of engineered cell and tissue products for use in patients. While these products are now technically advanced and better suited for the clinic, there continues to be issues around patient safety that need to be monitored and mitigated for routine use and mass production.
For the first time, the revolutionary gene-editing technology called CRISPR-Cas9 was used to repair a disease-causing genetic flaw in viable human embryos and prevent the mutation from being passed to future generations.
A new nuclease inhibitor drug program could lead to the commercialization of novel DNA damage response (DDR) treatments for female breast, ovarian, and other types of cancers.